Experimental Pharmacology: Principles and Applications is a practical academic guide to the experimental methods used to study drug action, pharmacodynamics, pharmacokinetics, efficacy, safety, and preclinical evaluation. Structured around laboratory-oriented learning, the book combines theoretical foundations with experimental procedures, laboratory animals, physiological preparations, pharmacological apparatus, bioassays, dose-response relationships, and established drug-screening models. Its 30-topic progression supports systematic learning from core laboratory principles to practical evaluation of drugs affecting different physiological systems.
It will enable you to:
Understand the scope, objectives, and foundations of experimental pharmacology.
Study commonly used laboratory animals, their handling, housing, diet, physiology, and research applications.
Understand physiological salt solutions such as Ringer’s, Tyrode’s, Krebs, and De Jalon’s solutions.
Become familiar with organ baths, kymographs, Rotarod, elevated plus maze, electroconvulsiometer, and actophotometer.
Learn anaesthesia, routes of drug administration, preclinical experiments, and blood-collection techniques.
Construct and interpret dose-response curves for acetylcholine and histamine.
Understand agonists, antagonists, EC50, potency estimation, and pharmacological bioassays.
Study interpolation and three-point bioassay methods with experimental calculations.
